Investigation on Supercritical CO2 Extraction of Black Nightshade Berries (Solanum nigrum Linn.)

A set of supercritical extractions (SCE) using carbon dioxide (CO2) has been performed on Solanum nigrum Linn. design experiment (DoE) Box-Behnken was applied to investigate the influential parameters SCE. The relationship between extraction (i.e., temperature, time, and pressure) products phenolics-TPC, alkaloids-TAC, flavonoids-TFC) evaluated. It found that temperature pressure are most influencing in Both give a synergistic effect increasing yield. optimum SCE conditions 333 K, 30 min, 240 bar; with extraction, yields expressed as TPC, TFC, TAC 55.1677 mg GAE/g extract, 28.0308 QE/g 5.9460 HYE/g respectively. Solubility data correlations were done by Chrastil’s model. adjustable model be consistent their physical meaning can